Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53 de...
Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53 deficient mammary cancers
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Publisher
England: The Company of Biologists Ltd
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Language
English
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Publisher
England: The Company of Biologists Ltd
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Contents
Targeted therapies against basal-like breast tumors, which are typically ‘triple negative breast cancers (TNBC)’, remain an important unmet clinical need. Somatic TP53 mutations are the most common genetic event in basal-like and TNBC breast tumors. To identify additional drivers and possible drug targets of this subtype, a comparative study betwee...
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Full title
Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53 deficient mammary cancers
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TN_cdi_doaj_primary_oai_doaj_org_article_99c2638bbc6a4e349d4cd81936b248eb
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_99c2638bbc6a4e349d4cd81936b248eb
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ISSN
1754-8403
E-ISSN
1754-8411
DOI
10.1242/dmm.025239
