Phase Ib evaluation of a self-adjuvanted protamine formulated mRNA-based active cancer immunotherapy...
Phase Ib evaluation of a self-adjuvanted protamine formulated mRNA-based active cancer immunotherapy, BI1361849 (CV9202), combined with local radiation treatment in patients with stage IV non-small cell lung cancer
About this item
Full title
Author / Creator
Papachristofilou, Alexandros , Hipp, Madeleine M. , Klinkhardt, Ute , Früh, Martin , Sebastian, Martin , Weiss, Christian , Pless, Miklos , Cathomas, Richard , Hilbe, Wolfgang , Pall, Georg , Wehler, Thomas , Alt, Jürgen , Bischoff, Helge , Geißler, Michael , Griesinger, Frank , Kallen, Karl-Josef , Fotin-Mleczek, Mariola , Schröder, Andreas , Scheel, Birgit , Muth, Anke , Seibel, Tobias , Stosnach, Claudia , Doener, Fatma , Hong, Henoch S. , Koch, Sven D. , Gnad-Vogt, Ulrike and Zippelius, Alfred
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Preclinical studies demonstrate synergism between cancer immunotherapy and local radiation, enhancing anti-tumor effects and promoting immune responses. BI1361849 (CV9202) is an active cancer immunotherapeutic comprising protamine-formulated, sequence-optimized mRNA encoding six non-small cell lung cancer (NSCLC)-associated antigens (NY-ESO-1, MAGE...
Alternative Titles
Full title
Phase Ib evaluation of a self-adjuvanted protamine formulated mRNA-based active cancer immunotherapy, BI1361849 (CV9202), combined with local radiation treatment in patients with stage IV non-small cell lung cancer
Authors, Artists and Contributors
Author / Creator
Hipp, Madeleine M.
Klinkhardt, Ute
Früh, Martin
Sebastian, Martin
Weiss, Christian
Pless, Miklos
Cathomas, Richard
Hilbe, Wolfgang
Pall, Georg
Wehler, Thomas
Alt, Jürgen
Bischoff, Helge
Geißler, Michael
Griesinger, Frank
Kallen, Karl-Josef
Fotin-Mleczek, Mariola
Schröder, Andreas
Scheel, Birgit
Muth, Anke
Seibel, Tobias
Stosnach, Claudia
Doener, Fatma
Hong, Henoch S.
Koch, Sven D.
Gnad-Vogt, Ulrike
Zippelius, Alfred
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_99e04455f1444be88b66a788433ed6e0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_99e04455f1444be88b66a788433ed6e0
Other Identifiers
ISSN
2051-1426
E-ISSN
2051-1426
DOI
10.1186/s40425-019-0520-5