IDH-wild type glioblastomas featuring at least 30% giant cells are characterized by frequent RB1 and...
IDH-wild type glioblastomas featuring at least 30% giant cells are characterized by frequent RB1 and NF1 alterations and hypermutation
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Giant cell glioblastoma (GC-GBM) is a rare variant of
IDH
-wt GBM histologically characterized by the presence of numerous multinucleated giant cells and molecularly considered a hybrid between
IDH
-wt and
IDH
-mutant GBM. The lack of an objective definition, specifying the percentage of giant cells required for this diagnosis, ma...
Alternative Titles
Full title
IDH-wild type glioblastomas featuring at least 30% giant cells are characterized by frequent RB1 and NF1 alterations and hypermutation
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TN_cdi_doaj_primary_oai_doaj_org_article_99e7b82f197643438e67e5c88a14ad33
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_99e7b82f197643438e67e5c88a14ad33
Other Identifiers
ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-021-01304-5
