USP9X-mediated REV1 deubiquitination promotes lung cancer radioresistance via the action of REV1 as...
USP9X-mediated REV1 deubiquitination promotes lung cancer radioresistance via the action of REV1 as a Rad18 molecular scaffold for cystathionine γ-lyase
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Author / Creator
Chen, Yunshang , Feng, Xue , Wu, Zilong , Yang, Yongqiang , Rao, Xinrui , Meng, Rui , Zhang, Sheng , Dong, Xiaorong , Xu, Shuangbing , Wu, Gang and Jie, Xiaohua
Publisher
England: BioMed Central
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central
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Scope and Contents
Contents
Radioresistance is a key clinical constraint on the efficacy of radiotherapy in lung cancer patients. REV1 DNA directed polymerase (REV1) plays an important role in repairing DNA damage and maintaining genomic stability. However, its role in the resistance to radiotherapy in lung cancer is not clear. This study aims to clarify the role of REV1 in l...
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Full title
USP9X-mediated REV1 deubiquitination promotes lung cancer radioresistance via the action of REV1 as a Rad18 molecular scaffold for cystathionine γ-lyase
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9a17e0830ff24a45930d6874330c15a4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9a17e0830ff24a45930d6874330c15a4
Other Identifiers
ISSN
1423-0127,1021-7770
E-ISSN
1423-0127
DOI
10.1186/s12929-024-01044-3
