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Membrane estrogen receptor alpha (ERα) participates in flow-mediated dilation in a ligand-independen...

Membrane estrogen receptor alpha (ERα) participates in flow-mediated dilation in a ligand-independen...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9a36969e61414a318a017f8e1eddcd91

Membrane estrogen receptor alpha (ERα) participates in flow-mediated dilation in a ligand-independent manner

About this item

Full title

Membrane estrogen receptor alpha (ERα) participates in flow-mediated dilation in a ligand-independent manner

Publisher

England: eLife Sciences Publications Ltd

Journal title

eLife, 2021-11, Vol.10

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

Estrogen receptor alpha (ERα) activation by estrogens prevents atheroma through its nuclear action, whereas plasma membrane-located ERα accelerates endothelial healing. The genetic deficiency of ERα was associated with a reduction in flow-mediated dilation (FMD) in one man. Here, we evaluated ex vivo the role of ERα on FMD of resistance arteries. F...

Alternative Titles

Full title

Membrane estrogen receptor alpha (ERα) participates in flow-mediated dilation in a ligand-independent manner

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_9a36969e61414a318a017f8e1eddcd91

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9a36969e61414a318a017f8e1eddcd91

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.68695

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