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Complete microtubule–kinetochore occupancy favours the segregation of merotelic attachments

Complete microtubule–kinetochore occupancy favours the segregation of merotelic attachments

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9a3a7d104da04b9aaaf96e0d29c5129d

Complete microtubule–kinetochore occupancy favours the segregation of merotelic attachments

About this item

Full title

Complete microtubule–kinetochore occupancy favours the segregation of merotelic attachments

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2018-05, Vol.9 (1), p.2042-16, Article 2042

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Kinetochores are multi-protein complexes that power chromosome movements by tracking microtubules plus-ends in the mitotic spindle. Human kinetochores bind up to 20 microtubules, even though single microtubules can generate sufficient force to move chromosomes. Here, we show that high microtubule occupancy at kinetochores ensures robust chromosome...

Alternative Titles

Full title

Complete microtubule–kinetochore occupancy favours the segregation of merotelic attachments

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_9a3a7d104da04b9aaaf96e0d29c5129d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9a3a7d104da04b9aaaf96e0d29c5129d

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-018-04427-x

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