The study of targeted blocking SDF-1/CXCR4 signaling pathway with three antagonists on MMPs, type II...
The study of targeted blocking SDF-1/CXCR4 signaling pathway with three antagonists on MMPs, type II collagen, and aggrecan levels in articular cartilage of guinea pigs
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
To explore the possibility and mechanism of targeted blocking SDF-1/CXCR4 signaling pathway using three antagonists TN14003, T140, and AMD3100 in vivo, and to investigate the function of three antagonists in delay degeneration process of articular cartilage.
Ninety-six male Duncan-Hartley guinea pigs (6 months old) were divided into groups A, B,...
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Full title
The study of targeted blocking SDF-1/CXCR4 signaling pathway with three antagonists on MMPs, type II collagen, and aggrecan levels in articular cartilage of guinea pigs
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TN_cdi_doaj_primary_oai_doaj_org_article_9a453747209243958e62b9dd17cd4812
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9a453747209243958e62b9dd17cd4812
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ISSN
1749-799X
E-ISSN
1749-799X
DOI
10.1186/s13018-020-01646-1
