A Novel Oncolytic Chimeric Orthopoxvirus Encoding Luciferase Enables Real-Time View of Colorectal Ca...
A Novel Oncolytic Chimeric Orthopoxvirus Encoding Luciferase Enables Real-Time View of Colorectal Cancer Cell Infection
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Publisher
United States: Elsevier Inc
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Language
English
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Publisher
United States: Elsevier Inc
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This study hypothesizes that a novel oncolytic chimeric orthopoxvirus CF33-Fluc is imageable and targets colorectal cancer cells (CRCs). A novel chimeric orthopoxvirus (CF33) was constructed. The thymidine kinase locus was replaced with firefly luciferase (Fluc) to yield a recombinant virus—CF33-Fluc. In vitro cytotoxicity and viral replication ass...
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A Novel Oncolytic Chimeric Orthopoxvirus Encoding Luciferase Enables Real-Time View of Colorectal Cancer Cell Infection
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TN_cdi_doaj_primary_oai_doaj_org_article_9a4bd410f1fc43c7b6e945ef430499b9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9a4bd410f1fc43c7b6e945ef430499b9
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ISSN
2372-7705
E-ISSN
2372-7705
DOI
10.1016/j.omto.2018.03.001
