Turning the respiratory flexibility of Mycobacterium tuberculosis against itself
Turning the respiratory flexibility of Mycobacterium tuberculosis against itself
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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The
Mycobacterium tuberculosis
(Mtb) electron transport chain (ETC) has received significant attention as a drug target, however its vulnerability may be affected by its flexibility in response to disruption. Here we determine the effect of the ETC inhibitors bedaquiline, Q203 and clofazimine on the Mtb ETC, and the value of the ETC as a drug...
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Turning the respiratory flexibility of Mycobacterium tuberculosis against itself
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TN_cdi_doaj_primary_oai_doaj_org_article_9a86dfe38a8246cd9d09bf2f836eeae4
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9a86dfe38a8246cd9d09bf2f836eeae4
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms12393