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Turning the respiratory flexibility of Mycobacterium tuberculosis against itself

Turning the respiratory flexibility of Mycobacterium tuberculosis against itself

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9a86dfe38a8246cd9d09bf2f836eeae4

Turning the respiratory flexibility of Mycobacterium tuberculosis against itself

About this item

Full title

Turning the respiratory flexibility of Mycobacterium tuberculosis against itself

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2016-08, Vol.7 (1), p.12393-14, Article 12393

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The
Mycobacterium tuberculosis
(Mtb) electron transport chain (ETC) has received significant attention as a drug target, however its vulnerability may be affected by its flexibility in response to disruption. Here we determine the effect of the ETC inhibitors bedaquiline, Q203 and clofazimine on the Mtb ETC, and the value of the ETC as a drug...

Alternative Titles

Full title

Turning the respiratory flexibility of Mycobacterium tuberculosis against itself

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_9a86dfe38a8246cd9d09bf2f836eeae4

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9a86dfe38a8246cd9d09bf2f836eeae4

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms12393

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