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Adenoviral delivery of the CIITA transgene induces T‐cell‐mediated killing in glioblastoma organoids

Adenoviral delivery of the CIITA transgene induces T‐cell‐mediated killing in glioblastoma organoids

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9aa61911a5b9469e8995daf03f7fc5d2

Adenoviral delivery of the CIITA transgene induces T‐cell‐mediated killing in glioblastoma organoids

About this item

Full title

Adenoviral delivery of the CIITA transgene induces T‐cell‐mediated killing in glioblastoma organoids

Publisher

United States: John Wiley & Sons, Inc

Journal title

Molecular oncology, 2025-03, Vol.19 (3), p.682-697

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

The immunosuppressive nature of the tumor microenvironment poses a significant challenge to effective immunotherapies against glioblastoma (GB). Boosting the immune response is critical for successful therapy. Here, we adopted a cancer gene therapy approach to induce T‐cell‐mediated killing of the tumor through increased activation of the immune sy...

Alternative Titles

Full title

Adenoviral delivery of the CIITA transgene induces T‐cell‐mediated killing in glioblastoma organoids

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_9aa61911a5b9469e8995daf03f7fc5d2

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9aa61911a5b9469e8995daf03f7fc5d2

Other Identifiers

ISSN

1574-7891,1878-0261

E-ISSN

1878-0261

DOI

10.1002/1878-0261.13750

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