Molecular model of prion transmission to humans
Molecular model of prion transmission to humans
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Publisher
United States: U.S. National Center for Infectious Diseases
Journal title
Language
English
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Publisher
United States: U.S. National Center for Infectious Diseases
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Contents
To assess interspecies barriers to transmission of transmissible spongiform encephalopathies, we investigated the ability of disease-associated prion proteins (PrPd) to initiate conversion of the human normal cellular form of prion protein of the 3 major PRNP polymorphic variants in vitro. Protein misfolding cyclic amplification showed that conform...
Alternative Titles
Full title
Molecular model of prion transmission to humans
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TN_cdi_doaj_primary_oai_doaj_org_article_9ab5598c1ac248f2a95b1d743374ca1d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9ab5598c1ac248f2a95b1d743374ca1d
Other Identifiers
ISSN
1080-6040
E-ISSN
1080-6059
DOI
10.3201/eid1512.090194
