Merging metabolic modeling and imaging for screening therapeutic targets in colorectal cancer
Merging metabolic modeling and imaging for screening therapeutic targets in colorectal cancer
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Cancer-associated fibroblasts (CAFs) play a key role in metabolic reprogramming and are well-established contributors to drug resistance in colorectal cancer (CRC). To exploit this metabolic crosstalk, we integrated a systems biology approach that identified key metabolic targets in a data-driven method and validated them experimentally. This proce...
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Merging metabolic modeling and imaging for screening therapeutic targets in colorectal cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_9adbc84446124443935660fef3357853
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9adbc84446124443935660fef3357853
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ISSN
2056-7189
E-ISSN
2056-7189
DOI
10.1038/s41540-025-00494-1
