Sumoylation regulates the assembly and activity of the SMN complex
Sumoylation regulates the assembly and activity of the SMN complex
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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SMN is a ubiquitously expressed protein and is essential for life. SMN deficiency causes the neurodegenerative disease spinal muscular atrophy (SMA), the leading genetic cause of infant mortality. SMN interacts with itself and other proteins to form a complex that functions in the assembly of ribonucleoproteins. SMN is modified by SUMO (Small Ubiqu...
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Sumoylation regulates the assembly and activity of the SMN complex
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TN_cdi_doaj_primary_oai_doaj_org_article_9ae40bf770e34a49910b6f8f9467d2e2
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9ae40bf770e34a49910b6f8f9467d2e2
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-25272-5
