Identification of Potential Inhibitors for the Treatment of Alkaptonuria Using an Integrated In Sili...
Identification of Potential Inhibitors for the Treatment of Alkaptonuria Using an Integrated In Silico Computational Strategy
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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Alkaptonuria (AKU) is a rare genetic autosomal recessive disorder characterized by elevated serum levels of homogentisic acid (HGA). In this disease, tyrosine metabolism is interrupted because of the alterations in homogentisate dioxygenase (HGD) gene. The patient suffers from ochronosis, fractures, and tendon ruptures. To date, no medicine has bee...
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Identification of Potential Inhibitors for the Treatment of Alkaptonuria Using an Integrated In Silico Computational Strategy
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TN_cdi_doaj_primary_oai_doaj_org_article_9b0d7a0463084a56b73fb687c8e00741
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9b0d7a0463084a56b73fb687c8e00741
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules28062623