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Design, Synthesis and Various Bioactivity of Acylhydrazone-Containing Matrine Analogues

Design, Synthesis and Various Bioactivity of Acylhydrazone-Containing Matrine Analogues

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9b15a2951dd2431db6dcfc7fded453b1

Design, Synthesis and Various Bioactivity of Acylhydrazone-Containing Matrine Analogues

About this item

Full title

Design, Synthesis and Various Bioactivity of Acylhydrazone-Containing Matrine Analogues

Publisher

Switzerland: MDPI AG

Journal title

Molecules (Basel, Switzerland), 2023-05, Vol.28 (10), p.4163

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Compounds with acylhydrazone fragments contain amide and imine groups that can act as electron donors and acceptors, so they are easier to bind to biological targets and thus generally exhibit significant biological activity. In this work, acylhydrazone fragments were introduced to the C-14 or C-11 position of matrine, a natural alkaloid, aiming to...

Alternative Titles

Full title

Design, Synthesis and Various Bioactivity of Acylhydrazone-Containing Matrine Analogues

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_9b15a2951dd2431db6dcfc7fded453b1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9b15a2951dd2431db6dcfc7fded453b1

Other Identifiers

ISSN

1420-3049

E-ISSN

1420-3049

DOI

10.3390/molecules28104163

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