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Simple Synthesis of Modafinil Derivatives and Their Anti-inflammatory Activity

Simple Synthesis of Modafinil Derivatives and Their Anti-inflammatory Activity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9b18e2ed48414988892dd976b626bacf

Simple Synthesis of Modafinil Derivatives and Their Anti-inflammatory Activity

About this item

Full title

Simple Synthesis of Modafinil Derivatives and Their Anti-inflammatory Activity

Publisher

Switzerland: MDPI AG

Journal title

Molecules (Basel, Switzerland), 2012-09, Vol.17 (9), p.10446-10458

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Simple synthesis of modafinil derivatives and their biological activity are described. The key synthetic strategies involve substitution and coupling reactions. We determined the anti-inflammatory effects of modafinil derivatives in cultured BV2 cells by measuring the inhibition of nitrite production and expression of iNOS and COX-2 after LPS stimu...

Alternative Titles

Full title

Simple Synthesis of Modafinil Derivatives and Their Anti-inflammatory Activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_9b18e2ed48414988892dd976b626bacf

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9b18e2ed48414988892dd976b626bacf

Other Identifiers

ISSN

1420-3049

E-ISSN

1420-3049

DOI

10.3390/molecules170910446

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