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Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microgl...

Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microgl...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9b23d42179b04772af58b32c842c4a9a

Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer’s disease

About this item

Full title

Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer’s disease

Publisher

England: BioMed Central Ltd

Journal title

Molecular neurodegeneration, 2018-05, Vol.13 (1), p.24-24, Article 24

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Disease-associated-microglia (DAM) represent transcriptionally-distinct and neurodegeneration-specific microglial profiles with unclear significance in Alzheimer's disease (AD). An understanding of heterogeneity within DAM and their key regulators may guide pre-clinical experimentation and drug discovery.
Weighted co-expression network analysis...

Alternative Titles

Full title

Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer’s disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_9b23d42179b04772af58b32c842c4a9a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9b23d42179b04772af58b32c842c4a9a

Other Identifiers

ISSN

1750-1326

E-ISSN

1750-1326

DOI

10.1186/s13024-018-0254-8

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