Continuous Feeding Reduces the Generation of Metabolic Byproducts and Increases Antibodies Expressio...
Continuous Feeding Reduces the Generation of Metabolic Byproducts and Increases Antibodies Expression in Chinese Hamster Ovary-K1 Cells
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Basel: MDPI AG
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English
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Basel: MDPI AG
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Chinese hamster ovary (CHO) cells are the most important host system used for monoclonal antibody (mAb) expression. Moreover, the fed-batch culture mode is the most widely used method to increase mAb expression in CHO cells by increasing the amount of feed. However, a high amount of culture feed results in the production of metabolic byproducts. In...
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Continuous Feeding Reduces the Generation of Metabolic Byproducts and Increases Antibodies Expression in Chinese Hamster Ovary-K1 Cells
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TN_cdi_doaj_primary_oai_doaj_org_article_9b24b2fe9dc4465792da53c44a522cc2
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9b24b2fe9dc4465792da53c44a522cc2
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ISSN
2075-1729
E-ISSN
2075-1729
DOI
10.3390/life11090945