Synthesis, In Vitro Biological Evaluation and Molecular Modeling of Benzimidazole-Based Pyrrole/Pipe...
Synthesis, In Vitro Biological Evaluation and Molecular Modeling of Benzimidazole-Based Pyrrole/Piperidine Hybrids Derivatives as Potential Anti-Alzheimer Agents
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Benzimidazole-based pyrrole/piperidine analogs (
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) were synthesized and then screened for their acetylcholinesterase and butyrylcholinesterase activities. All the analogs showed good to moderate cholinesterase activities. Synthesized compounds (
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) were screened in cholinesterase enzyme inhibition assays and showed AChE activities in...
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Full title
Synthesis, In Vitro Biological Evaluation and Molecular Modeling of Benzimidazole-Based Pyrrole/Piperidine Hybrids Derivatives as Potential Anti-Alzheimer Agents
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TN_cdi_doaj_primary_oai_doaj_org_article_9b3eb65368d14b0aafb27989d703e974
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9b3eb65368d14b0aafb27989d703e974
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ISSN
1424-8247
E-ISSN
1424-8247
DOI
10.3390/ph17040410