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Population Pharmacokinetics of Isavuconazole in Critical Care Patients with COVID-19-Associated Pulm...

Population Pharmacokinetics of Isavuconazole in Critical Care Patients with COVID-19-Associated Pulm...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9b407aebdd44433a89e3b957174584bd

Population Pharmacokinetics of Isavuconazole in Critical Care Patients with COVID-19-Associated Pulmonary Aspergillosis and Monte Carlo Simulations of High Off-Label Doses

About this item

Full title

Population Pharmacokinetics of Isavuconazole in Critical Care Patients with COVID-19-Associated Pulmonary Aspergillosis and Monte Carlo Simulations of High Off-Label Doses

Publisher

Switzerland: MDPI AG

Journal title

Journal of fungi (Basel), 2023-02, Vol.9 (2), p.211

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Isavuconazole is a triazole antifungal agent recently recommended as first-line therapy for invasive pulmonary aspergillosis. With the COVID-19 pandemic, cases of COVID-19-associated pulmonary aspergillosis (CAPA) have been described with a prevalence ranging from 5 to 30%. We developed and validated a population pharmacokinetic (PKpop) model of is...

Alternative Titles

Full title

Population Pharmacokinetics of Isavuconazole in Critical Care Patients with COVID-19-Associated Pulmonary Aspergillosis and Monte Carlo Simulations of High Off-Label Doses

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_9b407aebdd44433a89e3b957174584bd

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9b407aebdd44433a89e3b957174584bd

Other Identifiers

ISSN

2309-608X

E-ISSN

2309-608X

DOI

10.3390/jof9020211

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