Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease...
Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients
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Author / Creator
Wu, Yiming , Gettler, Kyle , Kars, Meltem Ece , Giri, Mamta , Li, Dalin , Bayrak, Cigdem Sevim , Zhang, Peng , Jain, Aayushee , Maffucci, Patrick , Sabic, Ksenija , Van Vleck, Tielman , Nadkarni, Girish , Denson, Lee A. , Ostrer, Harry , Levine, Adam P. , Schiff, Elena R. , Segal, Anthony W. , Kugathasan, Subra , Stenson, Peter D. , Cooper, David N. , Philip Schumm, L. , Snapper, Scott , Daly, Mark J. , Haritunians, Talin , Duerr, Richard H. , Silverberg, Mark S. , Rioux, John D. , Brant, Steven R. , McGovern, Dermot P. B. , Cho, Judy H. and Itan, Yuval
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Inflammatory bowel disease (IBD) is a group of chronic digestive tract inflammatory conditions whose genetic etiology is still poorly understood. The incidence of IBD is particularly high among Ashkenazi Jews. Here, we identify 8 novel and plausible IBD-causing genes from the exomes of 4453 genetically identified Ashkenazi Jewish IBD cases (1734) a...
Alternative Titles
Full title
Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients
Authors, Artists and Contributors
Author / Creator
Gettler, Kyle
Kars, Meltem Ece
Giri, Mamta
Li, Dalin
Bayrak, Cigdem Sevim
Zhang, Peng
Jain, Aayushee
Maffucci, Patrick
Sabic, Ksenija
Van Vleck, Tielman
Nadkarni, Girish
Denson, Lee A.
Ostrer, Harry
Levine, Adam P.
Schiff, Elena R.
Segal, Anthony W.
Kugathasan, Subra
Stenson, Peter D.
Cooper, David N.
Philip Schumm, L.
Snapper, Scott
Daly, Mark J.
Haritunians, Talin
Duerr, Richard H.
Silverberg, Mark S.
Rioux, John D.
Brant, Steven R.
McGovern, Dermot P. B.
Cho, Judy H.
Itan, Yuval
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9b4ce2bc11f1400dba2682d34318447c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9b4ce2bc11f1400dba2682d34318447c
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-37849-3
