Cysteine Proteases and Mitochondrial Instability: A Possible Vicious Cycle in MS Myelin?
Cysteine Proteases and Mitochondrial Instability: A Possible Vicious Cycle in MS Myelin?
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Switzerland: Frontiers Research Foundation
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English
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Switzerland: Frontiers Research Foundation
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[...]alterations at the level of the AMS, triggered by aberrant stimuli like dysfunctional Ca2+ mobilization from the axoplasmic reticulum (Micu et al., 2018), Na+ homeostasis alterations (Inglese et al., 2010) and/or the pathological presence of axonal nanoruptures (Witte et al., 2019) (Figure 1B, a–c) may instigate an augmented myelinic Ca2+ entr...
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Cysteine Proteases and Mitochondrial Instability: A Possible Vicious Cycle in MS Myelin?
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TN_cdi_doaj_primary_oai_doaj_org_article_9b52618962b14c6ba49a241a1486e802
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9b52618962b14c6ba49a241a1486e802
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ISSN
1662-5102
E-ISSN
1662-5102
DOI
10.3389/fncel.2020.612383
