The intestinal microbiome and metabolome discern disease severity in cytotoxic T-lymphocyte-associat...
The intestinal microbiome and metabolome discern disease severity in cytotoxic T-lymphocyte-associated protein 4 deficiency
About this item
Full title
Author / Creator
Chandrasekaran, Prabha , Krausz, Máté , Han, Yu , Mitsuiki, Noriko , Gabrysch, Annemarie , Nöltner, Christina , Proietti, Michele , Heller, Theo , Grou, Caroline , Calderon, Virginie , Subramanian, Poorani , Jones, Drew R , Siu, Yik , Deming, Clayton , Conlan, Sean , Holland, Steven M , Segre, Julia A , Uzel, Gulbu , Grimbacher, Bodo and Falcone, Emilia Liana
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Cytotoxic T-lymphocyte-associated protein 4 deficiency (CTLA4-D) is an inborn error of immunity (IEI) caused by heterozygous mutations, and characterized by immune cell infiltration into the gut and other organs, leading to intestinal disease, immune dysregulation and autoimmunity. While regulatory T-cell dysfunction remains central to CTLA4-D immu...
Alternative Titles
Full title
The intestinal microbiome and metabolome discern disease severity in cytotoxic T-lymphocyte-associated protein 4 deficiency
Authors, Artists and Contributors
Author / Creator
Krausz, Máté
Han, Yu
Mitsuiki, Noriko
Gabrysch, Annemarie
Nöltner, Christina
Proietti, Michele
Heller, Theo
Grou, Caroline
Calderon, Virginie
Subramanian, Poorani
Jones, Drew R
Siu, Yik
Deming, Clayton
Conlan, Sean
Holland, Steven M
Segre, Julia A
Uzel, Gulbu
Grimbacher, Bodo
Falcone, Emilia Liana
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9b6e3698fa944c93af41ad90c4797eb7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9b6e3698fa944c93af41ad90c4797eb7
Other Identifiers
ISSN
2049-2618
E-ISSN
2049-2618
DOI
10.1186/s40168-025-02028-7
