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Evaluation of safety, pharmacokinetics, and pharmacodynamics of apixaban in pediatric subjects at ri...

Evaluation of safety, pharmacokinetics, and pharmacodynamics of apixaban in pediatric subjects at ri...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9b743f85d5894a23873a53859c560c40

Evaluation of safety, pharmacokinetics, and pharmacodynamics of apixaban in pediatric subjects at risk of venous or arterial thrombotic disorder

About this item

Full title

Evaluation of safety, pharmacokinetics, and pharmacodynamics of apixaban in pediatric subjects at risk of venous or arterial thrombotic disorder

Publisher

United States: John Wiley & Sons, Inc

Journal title

CPT: pharmacometrics and systems pharmacology, 2023-04, Vol.12 (4), p.500-512

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Apixaban is an oral small‐molecule, direct factor Xa (FXa) inhibitor approved in adults for treatment of deep vein thrombosis and pulmonary embolism, and for reducing risk of venous thromboembolism recurrence after initial anticoagulant therapy. This phase I study (NCT01707394) evaluated the pharmacokinetics (PKs), pharmacodynamics (PDs), and safet...

Alternative Titles

Full title

Evaluation of safety, pharmacokinetics, and pharmacodynamics of apixaban in pediatric subjects at risk of venous or arterial thrombotic disorder

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_9b743f85d5894a23873a53859c560c40

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9b743f85d5894a23873a53859c560c40

Other Identifiers

ISSN

2163-8306

E-ISSN

2163-8306

DOI

10.1002/psp4.12935

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