CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1
CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1
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Author / Creator
Xu, Junjie , Ji, Lin , Liang, Yuelong , Wan, Zhe , Zheng, Wei , Song, Xiaomin , Gorshkov, Kirill , Sun, Qiming , Lin, Hui , Zheng, Xueyong , Chen, Jiang , Jin, Ren-an , Liang, Xiao and Cai, Xiujun
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Sorafenib is the first-line chemotherapeutic therapy for advanced hepatocellular carcinoma (HCC). However, sorafenib resistance significantly limits its therapeutic efficacy, and the mechanisms underlying resistance have not been fully clarified. Here we report that a circular RNA, circRNA-SORE (a circular RNA upregulated in
so
rafenib-
re...
Alternative Titles
Full title
CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1
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TN_cdi_doaj_primary_oai_doaj_org_article_9bb4353dda9e4f869b1aa1e0821f61b6
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9bb4353dda9e4f869b1aa1e0821f61b6
Other Identifiers
ISSN
2059-3635,2095-9907
E-ISSN
2059-3635
DOI
10.1038/s41392-020-00375-5
