Potent MOR Agonists from 2'-Hydroxy-5,9-dimethyl- N -phenethyl Substituted-6,7-benzomorphans and fro...
Potent MOR Agonists from 2'-Hydroxy-5,9-dimethyl- N -phenethyl Substituted-6,7-benzomorphans and from C8-Hydroxy, Methylene and Methyl Derivatives of N -Phenethylnormetazocine
About this item
Full title
Author / Creator
Publisher
Switzerland: MDPI AG
Journal title
Language
English
Formats
Publication information
Publisher
Switzerland: MDPI AG
Subjects
More information
Scope and Contents
Contents
(-)-5,9-Dimethyl-6,7-benzomorphan (normetazocine) derivatives with a
-OH or
-F substituent in the aromatic ring of the
-phenethyl moiety were synthesized and found to have subnanomolar potency at MOR, and both were fully efficacious in vitro. These new compounds, (1
,5
,9
)-6,11-dimethyl-3-(2-fluorophenethyl)-1,2,3,4,5,6-hexahydro...
Alternative Titles
Full title
Potent MOR Agonists from 2'-Hydroxy-5,9-dimethyl- N -phenethyl Substituted-6,7-benzomorphans and from C8-Hydroxy, Methylene and Methyl Derivatives of N -Phenethylnormetazocine
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9bbb663c8248404c9ee45202cb61671a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9bbb663c8248404c9ee45202cb61671a
Other Identifiers
ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules28237709
