Sporadic Parkinson's disease derived neuronal cells show disease-specific mRNA and small RNA signatu...
Sporadic Parkinson's disease derived neuronal cells show disease-specific mRNA and small RNA signatures with abundant deregulation of piRNAs
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Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Contents
Differentiated neurons established via iPSCs from patients that suffer from familial Parkinson's disease (PD) have allowed insights into the mechanisms of neurodegeneration. In the larger cohort of patients with sporadic PD, iPSC based information on disease specific cellular phenotypes is rare. We asked whether differences may be present on genomi...
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Full title
Sporadic Parkinson's disease derived neuronal cells show disease-specific mRNA and small RNA signatures with abundant deregulation of piRNAs
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TN_cdi_doaj_primary_oai_doaj_org_article_9bc705bbdc794478a15e25e4938f2b62
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9bc705bbdc794478a15e25e4938f2b62
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ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-018-0561-x
