A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and ep...
A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation
About this item
Full title
Author / Creator
Sheng, Chao , Jungverdorben, Johannes , Wiethoff, Hendrik , Lin, Qiong , Flitsch, Lea J. , Eckert, Daniela , Hebisch, Matthias , Fischer, Julia , Kesavan, Jaideep , Weykopf, Beatrice , Schneider, Linda , Holtkamp, Dominik , Beck, Heinz , Till, Andreas , Wüllner, Ullrich , Ziller, Michael J. , Wagner, Wolfgang , Peitz, Michael and Brüstle, Oliver
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Recent reports suggest that induced neurons (iNs), but not induced pluripotent stem cell (iPSC)-derived neurons, largely preserve age-associated traits. Here, we report on the extent of preserved epigenetic and transcriptional aging signatures in directly converted induced neural stem cells (iNSCs). Employing restricted and integration-free express...
Alternative Titles
Full title
A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation
Authors, Artists and Contributors
Author / Creator
Jungverdorben, Johannes
Wiethoff, Hendrik
Lin, Qiong
Flitsch, Lea J.
Eckert, Daniela
Hebisch, Matthias
Fischer, Julia
Kesavan, Jaideep
Weykopf, Beatrice
Schneider, Linda
Holtkamp, Dominik
Beck, Heinz
Till, Andreas
Wüllner, Ullrich
Ziller, Michael J.
Wagner, Wolfgang
Peitz, Michael
Brüstle, Oliver
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9c09e47ee2e347998c07481693058095
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9c09e47ee2e347998c07481693058095
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-06398-5
