CTLA-4 expressing innate lymphoid cells modulate mucosal homeostasis in a microbiota dependent manne...
CTLA-4 expressing innate lymphoid cells modulate mucosal homeostasis in a microbiota dependent manner
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Author / Creator
Lo, Jonathan W. , Schroeder, Jan-Hendrik , Roberts, Luke B. , Mohamed, Rami , Cozzetto, Domenico , Beattie, Gordon , Omer, Omer S. , Ross, Ellen M. , Heuts, Frank , Jowett, Geraldine M. , Read, Emily , Madgwick, Matthew , Neves, Joana F. , Korcsmaros, Tamas , Jenner, Richard G. , Walker, Lucy S. K. , Powell, Nick and Lord, Graham M.
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The maintenance of intestinal homeostasis is a fundamental process critical for organismal integrity. Sitting at the interface of the gut microbiome and mucosal immunity, adaptive and innate lymphoid populations regulate the balance between commensal micro-organisms and pathogens. Checkpoint inhibitors, particularly those targeting the CTLA-4 pathw...
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Full title
CTLA-4 expressing innate lymphoid cells modulate mucosal homeostasis in a microbiota dependent manner
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TN_cdi_doaj_primary_oai_doaj_org_article_9c1706884f1e46cd8fa10a092e27a500
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9c1706884f1e46cd8fa10a092e27a500
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-51719-6