Safety and antitumor activity of GD2-Specific 4SCAR-T cells in patients with glioblastoma
Safety and antitumor activity of GD2-Specific 4SCAR-T cells in patients with glioblastoma
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Author / Creator
Liu, Zhuohao , Zhou, Jiayi , Yang, Xinzhi , Liu, Yuchen , Zou, Chang , Lv, Wen , Chen, Cheng , Cheng, Kenneth King-yip , Chen, Tao , Chang, Lung-Ji , Wu, Dinglan and Mao, Jie
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
This study aimed to validate whether infusion of GD2-specific fourth-generation safety-designed chimeric antigen receptor (4SCAR)-T cells is safe and whether CAR-T cells exert anti-glioblastoma (GBM) activity.
A total of eight patients with GD2-positive GBM were enrolled and infused with autologous GD2-specific 4SCAR-T cells, either through intr...
Alternative Titles
Full title
Safety and antitumor activity of GD2-Specific 4SCAR-T cells in patients with glioblastoma
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9c4170e5fac24876802eeade1e6638be
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9c4170e5fac24876802eeade1e6638be
Other Identifiers
ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-022-01711-9
