Activity dependent LoNA regulates translation by coordinating rRNA transcription and methylation
Activity dependent LoNA regulates translation by coordinating rRNA transcription and methylation
About this item
Full title
Author / Creator
Li, Dingfeng , Zhang, Juan , Wang, Ming , Li, Xiaohui , Gong, Huarui , Tang, Huiping , Chen, Lin , Wan, Lili and Liu, Qiang
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
The ribosome is indispensable for precisely controlling the capacity of protein synthesis. However, how translational machinery is coordinated to meet the translational demands remains elusive. Here, we identify a nucleolar-specific lncRNA (LoNA), its 5′ portion binds and sequesters nucleolin to suppress rRNA transcription, and its snoRNA like 3′ e...
Alternative Titles
Full title
Activity dependent LoNA regulates translation by coordinating rRNA transcription and methylation
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9c46dff0d82944de8252c3ecb5fd350c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9c46dff0d82944de8252c3ecb5fd350c
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-04072-4
