Release of human cytomegalovirus from latency by a KAP1/TRIM28 phosphorylation switch
Release of human cytomegalovirus from latency by a KAP1/TRIM28 phosphorylation switch
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England: eLife Sciences Publications Ltd
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English
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England: eLife Sciences Publications Ltd
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Human cytomegalovirus (HCMV) is a highly prevalent pathogen that induces life-long infections notably through the establishment of latency in hematopoietic stem cells (HSC). Bouts of reactivation are normally controlled by the immune system, but can be fatal in immuno-compromised individuals such as organ transplant recipients. Here, we reveal that...
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Release of human cytomegalovirus from latency by a KAP1/TRIM28 phosphorylation switch
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TN_cdi_doaj_primary_oai_doaj_org_article_9c6d029a22c640eaa737dfe499233be6
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9c6d029a22c640eaa737dfe499233be6
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.06068