In vitro sepsis induces Nociceptin/Orphanin FQ receptor (NOP) expression in primary human vascular e...
In vitro sepsis induces Nociceptin/Orphanin FQ receptor (NOP) expression in primary human vascular endothelial but not smooth muscle cells
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Public Library of Science (PLoS)
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English
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Public Library of Science (PLoS)
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Sepsis is a dysregulated host response to infection that can cause widespread effects on other organs including cardiovascular depression, hypotension and organ failure. The receptor for Nociceptin/Orphanin FQ (N/OFQ), NOP is expressed on immune cells and these cells can release the peptide. Exogenous N/OFQ can dilate blood vessels and this peptide...
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In vitro sepsis induces Nociceptin/Orphanin FQ receptor (NOP) expression in primary human vascular endothelial but not smooth muscle cells
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TN_cdi_doaj_primary_oai_doaj_org_article_9c6ee19a704e489aa1cb76aea8f0b547
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9c6ee19a704e489aa1cb76aea8f0b547
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1932-6203
DOI
10.1371/journal.pone.0274080