Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity
Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity
About this item
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Author / Creator
Raj, Prithvi , Rai, Ekta , Song, Ran , Khan, Shaheen , Wakeland, Benjamin E , Viswanathan, Kasthuribai , Arana, Carlos , Liang, Chaoying , Zhang, Bo , Dozmorov, Igor , Carr-Johnson, Ferdicia , Mitrovic, Mitja , Wiley, Graham B , Kelly, Jennifer A , Lauwerys, Bernard R , Olsen, Nancy J , Cotsapas, Chris , Garcia, Christine K , Wise, Carol A , Harley, John B , Nath, Swapan K , James, Judith A , Jacob, Chaim O , Tsao, Betty P , Pasare, Chandrashekhar , Karp, David R , Li, Quan Zhen , Gaffney, Patrick M and Wakeland, Edward K
Publisher
England: eLife Sciences Publications Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: eLife Sciences Publications Ltd
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More information
Scope and Contents
Contents
Targeted sequencing of sixteen SLE risk loci among 1349 Caucasian cases and controls produced a comprehensive dataset of the variations causing susceptibility to systemic lupus erythematosus (SLE). Two independent disease association signals in the HLA-D region identified two regulatory regions containing 3562 polymorphisms that modified thirty-sev...
Alternative Titles
Full title
Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity
Authors, Artists and Contributors
Author / Creator
Rai, Ekta
Song, Ran
Khan, Shaheen
Wakeland, Benjamin E
Viswanathan, Kasthuribai
Arana, Carlos
Liang, Chaoying
Zhang, Bo
Dozmorov, Igor
Carr-Johnson, Ferdicia
Mitrovic, Mitja
Wiley, Graham B
Kelly, Jennifer A
Lauwerys, Bernard R
Olsen, Nancy J
Cotsapas, Chris
Garcia, Christine K
Wise, Carol A
Harley, John B
Nath, Swapan K
James, Judith A
Jacob, Chaim O
Tsao, Betty P
Pasare, Chandrashekhar
Karp, David R
Li, Quan Zhen
Gaffney, Patrick M
Wakeland, Edward K
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9cb126754a5c4c41a78ee8db59f27c5a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9cb126754a5c4c41a78ee8db59f27c5a
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.12089
