Log in to save to my catalogue

Alterations in the p53 isoform ratio govern breast cancer cell fate in response to DNA damage

Alterations in the p53 isoform ratio govern breast cancer cell fate in response to DNA damage

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9cb81a5c712a40c4a75be9cdbbd0bfac

Alterations in the p53 isoform ratio govern breast cancer cell fate in response to DNA damage

About this item

Full title

Alterations in the p53 isoform ratio govern breast cancer cell fate in response to DNA damage

Publisher

London: Nature Publishing Group UK

Journal title

Cell death & disease, 2022-10, Vol.13 (10), p.907-18, Article 907

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Our previous studies have shown that p53 isoform expression is altered in breast cancer and related to prognosis. In particular, a high ∆40p53:p53α ratio is associated with worse disease-free survival. In this manuscript, the influence of altered Δ40p53 and p53α levels on the response to standard of care DNA-damaging agents used in breast cancer tr...

Alternative Titles

Full title

Alterations in the p53 isoform ratio govern breast cancer cell fate in response to DNA damage

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_9cb81a5c712a40c4a75be9cdbbd0bfac

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9cb81a5c712a40c4a75be9cdbbd0bfac

Other Identifiers

ISSN

2041-4889

E-ISSN

2041-4889

DOI

10.1038/s41419-022-05349-9

How to access this item