Alterations in the p53 isoform ratio govern breast cancer cell fate in response to DNA damage
Alterations in the p53 isoform ratio govern breast cancer cell fate in response to DNA damage
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Our previous studies have shown that p53 isoform expression is altered in breast cancer and related to prognosis. In particular, a high ∆40p53:p53α ratio is associated with worse disease-free survival. In this manuscript, the influence of altered Δ40p53 and p53α levels on the response to standard of care DNA-damaging agents used in breast cancer tr...
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Alterations in the p53 isoform ratio govern breast cancer cell fate in response to DNA damage
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TN_cdi_doaj_primary_oai_doaj_org_article_9cb81a5c712a40c4a75be9cdbbd0bfac
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9cb81a5c712a40c4a75be9cdbbd0bfac
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2041-4889
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2041-4889
DOI
10.1038/s41419-022-05349-9