Functional hypoxia drives neuroplasticity and neurogenesis via brain erythropoietin
Functional hypoxia drives neuroplasticity and neurogenesis via brain erythropoietin
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Author / Creator
Wakhloo, Debia , Scharkowski, Franziska , Curto, Yasmina , Javed Butt, Umer , Bansal, Vikas , Steixner-Kumar, Agnes A. , Wüstefeld, Liane , Rajput, Ashish , Arinrad, Sahab , Zillmann, Matthias R. , Seelbach, Anna , Hassouna, Imam , Schneider, Katharina , Qadir Ibrahim, Abdul , Werner, Hauke B. , Martens, Henrik , Miskowiak, Kamilla , Wojcik, Sonja M. , Bonn, Stefan , Nacher, Juan , Nave, Klaus-Armin and Ehrenreich, Hannelore
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Erythropoietin (EPO), named after its role in hematopoiesis, is also expressed in mammalian brain. In clinical settings, recombinant EPO treatment has revealed a remarkable improvement of cognition, but underlying mechanisms have remained obscure. Here, we show with a novel line of reporter mice that cognitive challenge induces local/endogenous hyp...
Alternative Titles
Full title
Functional hypoxia drives neuroplasticity and neurogenesis via brain erythropoietin
Authors, Artists and Contributors
Author / Creator
Scharkowski, Franziska
Curto, Yasmina
Javed Butt, Umer
Bansal, Vikas
Steixner-Kumar, Agnes A.
Wüstefeld, Liane
Rajput, Ashish
Arinrad, Sahab
Zillmann, Matthias R.
Seelbach, Anna
Hassouna, Imam
Schneider, Katharina
Qadir Ibrahim, Abdul
Werner, Hauke B.
Martens, Henrik
Miskowiak, Kamilla
Wojcik, Sonja M.
Bonn, Stefan
Nacher, Juan
Nave, Klaus-Armin
Ehrenreich, Hannelore
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9d32af3f067e4d66a0725b72c12bd117
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9d32af3f067e4d66a0725b72c12bd117
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-15041-1
