Dual Targeting of Soluble Oligomeric and Aggregated Transthyretin with a Monoclonal Antibody Amelior...
Dual Targeting of Soluble Oligomeric and Aggregated Transthyretin with a Monoclonal Antibody Ameliorates Experimental Neuropathy
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Basel: MDPI AG
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English
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Basel: MDPI AG
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ATTR amyloidosis comprises a spectrum of multiple clinical presentations, including, predominantly, neuropathy and cardiomyopathy. The common triggering pathogenic protein is misfolded transthyretin, a carrier protein that destabilizes misfolds and assembles into mature amyloid fibrils. The current management of ATTR amyloidosis includes the use of...
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Full title
Dual Targeting of Soluble Oligomeric and Aggregated Transthyretin with a Monoclonal Antibody Ameliorates Experimental Neuropathy
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TN_cdi_doaj_primary_oai_doaj_org_article_9d8a5342b97848fe8f74f66c9d43be00
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9d8a5342b97848fe8f74f66c9d43be00
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ISSN
2079-7737
E-ISSN
2079-7737
DOI
10.3390/biology11101509
