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An osteosarcoma-on-a-chip model for studying osteosarcoma matrix-cell interactions and drug response...

An osteosarcoma-on-a-chip model for studying osteosarcoma matrix-cell interactions and drug response...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9d9aef118d7e4785856915061faa6455

An osteosarcoma-on-a-chip model for studying osteosarcoma matrix-cell interactions and drug responses

About this item

Full title

An osteosarcoma-on-a-chip model for studying osteosarcoma matrix-cell interactions and drug responses

Publisher

China: Elsevier B.V

Journal title

Bioactive materials, 2024-04, Vol.34, p.1-16

Language

English

Formats

Publication information

Publisher

China: Elsevier B.V

More information

Scope and Contents

Contents

Marrow niches in osteosarcoma (OS) are a specialized microenvironment that is essential for the maintenance and regulation of OS cells. However, existing animal xenograft models are plagued by variability, complexity, and high cost. Herein, we used a decellularized osteosarcoma extracellular matrix (dOsEM) loaded with extracellular vesicles from hu...

Alternative Titles

Full title

An osteosarcoma-on-a-chip model for studying osteosarcoma matrix-cell interactions and drug responses

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_9d9aef118d7e4785856915061faa6455

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9d9aef118d7e4785856915061faa6455

Other Identifiers

ISSN

2452-199X

E-ISSN

2452-199X

DOI

10.1016/j.bioactmat.2023.12.005

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