A maximum-entropy model to predict 3D structural ensembles of chromatin from pairwise distances with...
A maximum-entropy model to predict 3D structural ensembles of chromatin from pairwise distances with applications to interphase chromosomes and structural variants
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The principles that govern the organization of genomes, which are needed for an understanding of how chromosomes are packaged and function in eukaryotic cells, could be deciphered if the three-dimensional (3D) structures are known. Recently, single-cell imaging techniques have been developed to determine the 3D coordinates of genomic loci in vivo....
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A maximum-entropy model to predict 3D structural ensembles of chromatin from pairwise distances with applications to interphase chromosomes and structural variants
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TN_cdi_doaj_primary_oai_doaj_org_article_9dc4b6448f1546c59e125cdd8a7d09cf
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9dc4b6448f1546c59e125cdd8a7d09cf
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-36412-4
