Decapping protein EDC4 regulates DNA repair and phenocopies BRCA1
Decapping protein EDC4 regulates DNA repair and phenocopies BRCA1
About this item
Full title
Author / Creator
Hernández, Gonzalo , Ramírez, María José , Minguillón, Jordi , Quiles, Paco , Ruiz de Garibay, Gorka , Aza-Carmona, Miriam , Bogliolo, Massimo , Pujol, Roser , Prados-Carvajal, Rosario , Fernández, Juana , García, Nadia , López, Adrià , Gutiérrez-Enríquez, Sara , Diez, Orland , Benítez, Javier , Salinas, Mónica , Teulé, Alex , Brunet, Joan , Radice, Paolo , Peterlongo, Paolo , Schindler, Detlev , Huertas, Pablo , Puente, Xose S , Lázaro, Conxi , Pujana, Miquel Àngel and Surrallés, Jordi
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
BRCA1 is a tumor suppressor that regulates DNA repair by homologous recombination. Germline mutations in
BRCA1
are associated with increased risk of breast and ovarian cancer and BRCA1 deficient tumors are exquisitely sensitive to poly (ADP-ribose) polymerase (PARP) inhibitors. Therefore, uncovering additional components of this DNA repair pa...
Alternative Titles
Full title
Decapping protein EDC4 regulates DNA repair and phenocopies BRCA1
Authors, Artists and Contributors
Author / Creator
Ramírez, María José
Minguillón, Jordi
Quiles, Paco
Ruiz de Garibay, Gorka
Aza-Carmona, Miriam
Bogliolo, Massimo
Pujol, Roser
Prados-Carvajal, Rosario
Fernández, Juana
García, Nadia
López, Adrià
Gutiérrez-Enríquez, Sara
Diez, Orland
Benítez, Javier
Salinas, Mónica
Teulé, Alex
Brunet, Joan
Radice, Paolo
Peterlongo, Paolo
Schindler, Detlev
Huertas, Pablo
Puente, Xose S
Lázaro, Conxi
Pujana, Miquel Àngel
Surrallés, Jordi
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9dd58df3757244329f9ae097492e7706
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9dd58df3757244329f9ae097492e7706
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-03433-3
