Differential Genetic and Epigenetic Regulation of Catechol-O-Methyl-Transferase (COMT) is Associated...
Differential Genetic and Epigenetic Regulation of Catechol-O-Methyl-Transferase (COMT) is Associated with Impaired Fear Inhibition in Posttraumatic Stress Disorder
About this item
Full title
Author / Creator
Publisher
Frontiers Media S.A
Journal title
Language
English
Formats
Publication information
Publisher
Frontiers Media S.A
Subjects
More information
Scope and Contents
Contents
The catechol-O-methyltransferase (COMT) enzyme is critical for the catabolic regulation of synaptic dopamine, resulting in altered cortical functioning. The COMT Val158Met polymorphism has been implicated in human mental illness, with Met/Met homozygotes associated with increased susceptibility to posttraumatic stress disorder (PTSD). Our primary o...
Alternative Titles
Full title
Differential Genetic and Epigenetic Regulation of Catechol-O-Methyl-Transferase (COMT) is Associated with Impaired Fear Inhibition in Posttraumatic Stress Disorder
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9dd960e5e64c40c59760d99c799b82f1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9dd960e5e64c40c59760d99c799b82f1
Other Identifiers
E-ISSN
1662-5153
DOI
10.3389/fnbeh.2013.00030
