CMTr cap-adjacent 2′-O-ribose mRNA methyltransferases are required for reward learning and mRNA loca...
CMTr cap-adjacent 2′-O-ribose mRNA methyltransferases are required for reward learning and mRNA localization to synapses
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Publisher
London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
Cap-adjacent nucleotides of animal, protist and viral mRNAs can be
O
-methylated at the 2‘ position of the ribose (cOMe). The functions of cOMe in animals, however, remain largely unknown. Here we show that the two cap methyltransferases (CMTr1 and CMTr2) of
Drosophila
can methylate the ribose of the first nucleotide in mRNA. Double-mut...
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CMTr cap-adjacent 2′-O-ribose mRNA methyltransferases are required for reward learning and mRNA localization to synapses
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TN_cdi_doaj_primary_oai_doaj_org_article_9ddea6fc816144ce8ba3edac4847c01c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9ddea6fc816144ce8ba3edac4847c01c
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-28549-5
