Chromenol Derivatives as Novel Antifungal Agents: Synthesis, In Silico and In Vitro Evaluation
Chromenol Derivatives as Novel Antifungal Agents: Synthesis, In Silico and In Vitro Evaluation
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Author / Creator
Zveaghintseva, Marina , Stingaci, Eugenia , Pogrebnoi, Serghei , Smetanscaia, Anastasia , Valica, Vladimir , Uncu, Livia , Ch. Kravtsov, Victor , Melnic, Elena , Petrou, Anthi , Glamočlija, Jasmina , Soković, Marina , Carazo, Alejandro , Mladěnka, Přemysl , Poroikov, Vladimir , Geronikaki, Athina and Macaev, Fliur Z.
Publisher
Basel: MDPI AG
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Language
English
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Publisher
Basel: MDPI AG
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Contents
Herein we report the synthesis of some new 1H-1,2,4-triazole functionalized chromenols (3a–3n) via tandem reactions of 1-(alkyl/aryl)-2-(1H-1,2,4-triazole-1-yl) with salicylic aldehydes and the evaluation of their antifungal activity. In silico prediction of biological activity with computer program PASS indicate that the compounds have a high nove...
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Full title
Chromenol Derivatives as Novel Antifungal Agents: Synthesis, In Silico and In Vitro Evaluation
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9df929bfd0284073a33102735d381583
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9df929bfd0284073a33102735d381583
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules26144304
