Jagged1/Notch2 controls kidney fibrosis via Tfam-mediated metabolic reprogramming
Jagged1/Notch2 controls kidney fibrosis via Tfam-mediated metabolic reprogramming
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
While Notch signaling has been proposed to play a key role in fibrosis, the direct molecular pathways targeted by Notch signaling and the precise ligand and receptor pair that are responsible for kidney disease remain poorly defined. In this study, we found that JAG1 and NOTCH2 showed the strongest correlation with the degree of interstitial fibros...
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Full title
Jagged1/Notch2 controls kidney fibrosis via Tfam-mediated metabolic reprogramming
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TN_cdi_doaj_primary_oai_doaj_org_article_9e2933f335bb4d558b23529c6dbb299c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9e2933f335bb4d558b23529c6dbb299c
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ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.2005233
