CCL2-CCR2 axis recruits tumor associated macrophages to induce immune evasion through PD-1 signaling...
CCL2-CCR2 axis recruits tumor associated macrophages to induce immune evasion through PD-1 signaling in esophageal carcinogenesis
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Author / Creator
Yang, Hui , Zhang, Qiannan , Xu, Miao , Wang, Lei , Chen, Xuewei , Feng, Yongquan , Li, Yongning , Zhang, Xin , Cui, Wenming and Jia, Xudong
Publisher
England: BioMed Central Ltd
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Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
The poor prognosis of esophageal squamous cell carcinoma (ESCC) highlights the need for novel strategies against this disease. Our previous study suggested the involvement of CCL2 and tumor associated macrophages (TAMs) in esophageal carcinogenesis. Despite the recognition of TAMs as a promising target for cancer treatment, mechanisms underlying it...
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Full title
CCL2-CCR2 axis recruits tumor associated macrophages to induce immune evasion through PD-1 signaling in esophageal carcinogenesis
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9e55ab34f8a54466b61d1a15daa49ad1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9e55ab34f8a54466b61d1a15daa49ad1
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ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-020-01165-x