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CCL2-CCR2 axis recruits tumor associated macrophages to induce immune evasion through PD-1 signaling...

CCL2-CCR2 axis recruits tumor associated macrophages to induce immune evasion through PD-1 signaling...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9e55ab34f8a54466b61d1a15daa49ad1

CCL2-CCR2 axis recruits tumor associated macrophages to induce immune evasion through PD-1 signaling in esophageal carcinogenesis

About this item

Full title

CCL2-CCR2 axis recruits tumor associated macrophages to induce immune evasion through PD-1 signaling in esophageal carcinogenesis

Publisher

England: BioMed Central Ltd

Journal title

Molecular cancer, 2020-02, Vol.19 (1), p.41-14, Article 41

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

The poor prognosis of esophageal squamous cell carcinoma (ESCC) highlights the need for novel strategies against this disease. Our previous study suggested the involvement of CCL2 and tumor associated macrophages (TAMs) in esophageal carcinogenesis. Despite the recognition of TAMs as a promising target for cancer treatment, mechanisms underlying it...

Alternative Titles

Full title

CCL2-CCR2 axis recruits tumor associated macrophages to induce immune evasion through PD-1 signaling in esophageal carcinogenesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_9e55ab34f8a54466b61d1a15daa49ad1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9e55ab34f8a54466b61d1a15daa49ad1

Other Identifiers

ISSN

1476-4598

E-ISSN

1476-4598

DOI

10.1186/s12943-020-01165-x

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