High activity and low toxicity of a novel CD71-targeting nanotherapeutic named The-0504 on preclinic...
High activity and low toxicity of a novel CD71-targeting nanotherapeutic named The-0504 on preclinical models of several human aggressive tumors
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Ferritin receptor (CD71) is an example of a very attractive cancer target, since it is highly expressed in virtually all tumor types, including metastatic loci. However, this target can be considered to be inaccessible to conventional target therapies, due to its presence in many healthy tissues. Here, we describe the preclinical evaluation of a tu...
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High activity and low toxicity of a novel CD71-targeting nanotherapeutic named The-0504 on preclinical models of several human aggressive tumors
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TN_cdi_doaj_primary_oai_doaj_org_article_9e69bc049eb0484e9987bd48a32027e6
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9e69bc049eb0484e9987bd48a32027e6
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1756-9966,0392-9078
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1756-9966
DOI
10.1186/s13046-021-01851-8