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High activity and low toxicity of a novel CD71-targeting nanotherapeutic named The-0504 on preclinic...

High activity and low toxicity of a novel CD71-targeting nanotherapeutic named The-0504 on preclinic...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9e69bc049eb0484e9987bd48a32027e6

High activity and low toxicity of a novel CD71-targeting nanotherapeutic named The-0504 on preclinical models of several human aggressive tumors

About this item

Full title

High activity and low toxicity of a novel CD71-targeting nanotherapeutic named The-0504 on preclinical models of several human aggressive tumors

Publisher

England: BioMed Central Ltd

Journal title

Journal of experimental & clinical cancer research, 2021-02, Vol.40 (1), p.63-14, Article 63

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Ferritin receptor (CD71) is an example of a very attractive cancer target, since it is highly expressed in virtually all tumor types, including metastatic loci. However, this target can be considered to be inaccessible to conventional target therapies, due to its presence in many healthy tissues. Here, we describe the preclinical evaluation of a tu...

Alternative Titles

Full title

High activity and low toxicity of a novel CD71-targeting nanotherapeutic named The-0504 on preclinical models of several human aggressive tumors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_9e69bc049eb0484e9987bd48a32027e6

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9e69bc049eb0484e9987bd48a32027e6

Other Identifiers

ISSN

1756-9966,0392-9078

E-ISSN

1756-9966

DOI

10.1186/s13046-021-01851-8

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