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iMyoblasts for ex vivo and in vivo investigations of human myogenesis and disease modeling

iMyoblasts for ex vivo and in vivo investigations of human myogenesis and disease modeling

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9ecae599191e4bdc9b10049699fefb2c

iMyoblasts for ex vivo and in vivo investigations of human myogenesis and disease modeling

About this item

Full title

iMyoblasts for ex vivo and in vivo investigations of human myogenesis and disease modeling

Publisher

England: eLife Sciences Publications Ltd

Journal title

eLife, 2022-01, Vol.11

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

Skeletal muscle myoblasts (iMyoblasts) were generated from human induced pluripotent stem cells (iPSCs) using an efficient and reliable transgene-free induction and stem cell selection protocol. Immunofluorescence, flow cytometry, qPCR, digital RNA expression profiling, and scRNA-Seq studies identify iMyoblasts as a
PAX3+/MYOD1+
skeletal myog...

Alternative Titles

Full title

iMyoblasts for ex vivo and in vivo investigations of human myogenesis and disease modeling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_9ecae599191e4bdc9b10049699fefb2c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9ecae599191e4bdc9b10049699fefb2c

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.70341

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