Patient-Derived Xenografts and Organoids Recapitulate Castration-Resistant Prostate Cancer with Sust...
Patient-Derived Xenografts and Organoids Recapitulate Castration-Resistant Prostate Cancer with Sustained Androgen Receptor Signaling
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Author / Creator
Van Hemelryk, Annelies , Tomljanovic, Ingrid , de Ridder, Corrina M. A. , Stuurman, Debra C. , Teubel, Wilma J. , Erkens-Schulze, Sigrun , Verhoef, Esther I. , Remmers, Sebastiaan , Mahes, Amrish J. , van Leenders, Geert J. L. H. , van Royen, Martin E. , van de Werken, Harmen J. G. , Grudniewska, Magda , Jenster, Guido W. and van Weerden, Wytske M.
Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publication information
Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
Castration-resistant prostate cancer (CRPC) remains an incurable and lethal malignancy. The development of new CRPC treatment strategies is strongly impeded by the scarcity of representative, scalable and transferable preclinical models of advanced, androgen receptor (AR)-driven CRPC. Here, we present contemporary patient-derived xenografts (PDXs)...
Alternative Titles
Full title
Patient-Derived Xenografts and Organoids Recapitulate Castration-Resistant Prostate Cancer with Sustained Androgen Receptor Signaling
Authors, Artists and Contributors
Author / Creator
Tomljanovic, Ingrid
de Ridder, Corrina M. A.
Stuurman, Debra C.
Teubel, Wilma J.
Erkens-Schulze, Sigrun
Verhoef, Esther I.
Remmers, Sebastiaan
Mahes, Amrish J.
van Leenders, Geert J. L. H.
van Royen, Martin E.
van de Werken, Harmen J. G.
Grudniewska, Magda
Jenster, Guido W.
van Weerden, Wytske M.
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9ed70a04355a4fed8481dd542b4ecb2b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9ed70a04355a4fed8481dd542b4ecb2b
Other Identifiers
ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells11223632