Taurine activates the AKT–mTOR axis to restore muscle mass and contractile strength in human 3D in v...
Taurine activates the AKT–mTOR axis to restore muscle mass and contractile strength in human 3D in vitro models of steroid myopathy
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Publisher
England: The Company of Biologists Ltd
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Language
English
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Publisher
England: The Company of Biologists Ltd
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Steroid myopathy is a clinically challenging condition exacerbated by prolonged corticosteroid use or adrenal tumors. In this study, we engineered a functional three-dimensional (3D) in vitro skeletal muscle model to investigate steroid myopathy. By subjecting our bioengineered muscle tissues to dexamethasone treatment, we reproduced the molecular...
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Full title
Taurine activates the AKT–mTOR axis to restore muscle mass and contractile strength in human 3D in vitro models of steroid myopathy
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TN_cdi_doaj_primary_oai_doaj_org_article_9ee84af3b7c445c4ae068a0ad9e849f4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9ee84af3b7c445c4ae068a0ad9e849f4
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ISSN
1754-8403
E-ISSN
1754-8411
DOI
10.1242/dmm.050540
