The Prognostic and Predictive Role of Somatic BRCA Mutations in Ovarian Cancer: Results from a Multi...
The Prognostic and Predictive Role of Somatic BRCA Mutations in Ovarian Cancer: Results from a Multicenter Cohort Study
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Author / Creator
Toss, Angela , Piombino, Claudia , Tenedini, Elena , Bologna, Alessandra , Gasparini, Elisa , Tarantino, Vittoria , Filieri, Maria Elisabetta , Cottafavi, Luca , Giovanardi, Filippo , Madrigali, Stefano , Civallero, Monica , Marcheselli, Luigi , Marchi, Isabella , Domati, Federica , Venturelli, Marta , Barbieri, Elena , Grandi, Giovanni , Tagliafico, Enrico and Cortesi, Laura
Publisher
Switzerland: MDPI
Journal title
Language
English
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Publisher
Switzerland: MDPI
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Scope and Contents
Contents
Previous research involving epithelial ovarian cancer patients showed that, compared to germline
(gBRCA) mutations, somatic
(sBRCA) mutations present a similar positive impact with regard to overall survival (OS) and platinum and PARP (poly (ADP-ribose) polymerase) inhibitor sensitivity. Nevertheless, molecular testing in these studies did no...
Alternative Titles
Full title
The Prognostic and Predictive Role of Somatic BRCA Mutations in Ovarian Cancer: Results from a Multicenter Cohort Study
Authors, Artists and Contributors
Author / Creator
Piombino, Claudia
Tenedini, Elena
Bologna, Alessandra
Gasparini, Elisa
Tarantino, Vittoria
Filieri, Maria Elisabetta
Cottafavi, Luca
Giovanardi, Filippo
Madrigali, Stefano
Civallero, Monica
Marcheselli, Luigi
Marchi, Isabella
Domati, Federica
Venturelli, Marta
Barbieri, Elena
Grandi, Giovanni
Tagliafico, Enrico
Cortesi, Laura
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9eec5d9a9b4f45449325e2c0246903d7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9eec5d9a9b4f45449325e2c0246903d7
Other Identifiers
ISSN
2075-4418
E-ISSN
2075-4418
DOI
10.3390/diagnostics11030565