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The Prognostic and Predictive Role of Somatic BRCA Mutations in Ovarian Cancer: Results from a Multi...

The Prognostic and Predictive Role of Somatic BRCA Mutations in Ovarian Cancer: Results from a Multi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9eec5d9a9b4f45449325e2c0246903d7

The Prognostic and Predictive Role of Somatic BRCA Mutations in Ovarian Cancer: Results from a Multicenter Cohort Study

About this item

Full title

The Prognostic and Predictive Role of Somatic BRCA Mutations in Ovarian Cancer: Results from a Multicenter Cohort Study

Publisher

Switzerland: MDPI

Journal title

Diagnostics (Basel), 2021-03, Vol.11 (3), p.565

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI

More information

Scope and Contents

Contents

Previous research involving epithelial ovarian cancer patients showed that, compared to germline
(gBRCA) mutations, somatic
(sBRCA) mutations present a similar positive impact with regard to overall survival (OS) and platinum and PARP (poly (ADP-ribose) polymerase) inhibitor sensitivity. Nevertheless, molecular testing in these studies did no...

Alternative Titles

Full title

The Prognostic and Predictive Role of Somatic BRCA Mutations in Ovarian Cancer: Results from a Multicenter Cohort Study

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_9eec5d9a9b4f45449325e2c0246903d7

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9eec5d9a9b4f45449325e2c0246903d7

Other Identifiers

ISSN

2075-4418

E-ISSN

2075-4418

DOI

10.3390/diagnostics11030565

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